Protein Modification Reagents
Medchemexpress LLC Azido-PEG3-Val-Cit-PAB-PNP | 2055047-18-0 | 99.1% | 773.79 g/mol | C34H47N9O12 | 100 MG
Azido-PEG3-Val-Cit-PAB-PNP is an azide-functional PEG3 Val-Cit PAB cleavable linker designed for use in antibody-drug conjugate (ADC) assembly and in the construction of PROTAC linkers. It combines an azide handle for click chemistry with a PNP-activated PAB leaving group for efficient conjugation.
- Cleavable Val-Cit PAB dipeptide linker suitable for ADCs.
- Azide-functionalized for copper-catalyzed and strain-promoted click reactions.
- PEG3 spacer to improve hydrophilicity and linker flexibility.
- PNP-activated leaving group for efficient conjugation chemistry.
- Available in small-scale quantities including 100 mg for research use.
Medchemexpress LLC Biotin-PEG2-acid | 1365655-89-5 | MFCD22056305 | ≥97.0% | 403.49 g·mol⁻¹ | C17H29N3O6S | 250 MG
Biotin-PEG2-acid is a biotinylated polyethylene glycol linker with a terminal carboxylic acid, used as a non-cleavable ADC and PROTAC linker for bioconjugation, affinity labeling, and linker synthesis. It is supplied in small laboratory pack sizes for conjugation workflows.
- Biotinylated PEG linker with a terminal carboxylic acid for conjugation.
- Non-cleavable two-unit PEG spacer suited for ADC and PROTAC syntheses.
- High purity (≥97.0%) for reliable conjugation performance.
- Molecular weight 403.49 g·mol⁻¹; formula C17H29N3O6S.
- Available in small-scale quantities such as 250 MG.
- Store protected from light under argon at -20°C; in solvent store at -80°C for long-term.
Medchemexpress LLC 5,8-dioxa-2,11-diazatetradecanoic acid, 14-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-12-oxo... | 2675364-08-4 | 98.1% | 475.53 | C24H33N3O7 | 5 MG
BCN-endo-PEG2-maleimide is a bioconjugation reagent combining an endo-BCN strained alkyne and a maleimide thiol-reactive group linked by a PEG2 spacer. It is intended for antibody-drug conjugate (ADC) linker synthesis, click chemistry (SPAAC), and thiol conjugation in bioconjugation workflows.
- Provides strain-promoted azide-alkyne cycloaddition reactivity (endo-BCN)
- Contains a maleimide group for thiol-selective conjugation
- Short PEG2 spacer improves solubility and flexibility
- High purity suitable for research (purity 98.06%)
- Available in small pack sizes for conjugation optimization
Medchemexpress LLC Azido-PEG6-azide | 1243536-56-2 | 96.2% | 376.41 g/mol | C14H28N6O6 | 5 MG
Azido-PEG6-azide is a bifunctional PEG6 linker bearing azide groups at both termini, designed for click-chemistry conjugation and linker design in small-molecule and biomolecule synthesis. It is supplied for research use and provided in small, precisely measured packs for laboratory applications.
- Bifunctional PEG6 linker with azide groups at both ends.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation.
- Suitable for PROTAC linker synthesis and small-molecule conjugation.
- High purity (~96.2%) for reproducible synthetic results.
- Molecular weight 376.41 g/mol; formula C14H28N6O6.
- Available in small research packs, including a 5 mg option.
- Colorless to light yellow liquid; store sealed, away from moisture.
eMolecules 1393330-40-9 | Propargyl-PEG5-NHS ester | Broadpharm | MFCD22574798 | 401.412 | C18H27NO9 | 98.000 | O=C(CCOCCOCCOCCOCCOCC#C)ON1C(=O)CCC1=O | 100mg | 229582898
Propargyl-PEG5-NHS ester | Broadpharm | 1393330-40-9 | MFCD22574798 | 401.412 | C18H27NO9 | 98.000 | O=C(CCOCCOCCOCCOCCOCC#C)ON1C(=O)CCC1=O | 100mg | 229582898
eMolecules 1924596-31-5 | Mal-amido-PEG8-TFP ester | Broadpharm | MFCD28505514 | 740.699 | C32H44F4N2O13 | 98.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 500mg | 279709072
Mal-amido-PEG8-TFP ester | Broadpharm | 1924596-31-5 | MFCD28505514 | 740.699 | C32H44F4N2O13 | 98.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 500mg | 279709072
STA PHARMACEUTICAL US LLC Azide-PEG3-L-alanine-Fmoc | 10 g | CAS 2054345-69-4 | InChIKey YTHKPQSMRZQREU-JOCHJYFZSA-N
Azide-PEG3-L-alanine-Fmoc is a Amino Acid reagent (Subcategory: Azido/Alkynyl AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2054345-69-4
- MDL: No data
- InChIKey: YTHKPQSMRZQREU-JOCHJYFZSA-N
- Molecular Weight: 484.509
- Molecular Formula: C24H28N4O7
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-D-serine
- SMILES: O=C(N[C@H](COCCOCCOCCN=[N+]=[N-])C(O)=O)OCC1C2=C(C=CC=C2)C3=C1C=CC=C3
Medchemexpress LLC Bromoacetamido-PEG2-C2-NHS ester | 1353011-78-5 | 95.0% | C13H19BrN2O7 | 25 MG
Bromoacetamido-PEG2-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- Selectively degrades target proteins
eMolecules Bromo-PEG24-t-butyl ester | Broadpharm |1266.355 | C55H109BrO26 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCBr | 250mg | 452533439
Bromo-PEG24-t-butyl ester | Broadpharm |1266.355 | C55H109BrO26 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCBr | 250mg | 452533439
Medchemexpress LLC DBCO-(PEG)3-VC-PAB-MMAE | 2754384-60-4 | 99.60% | 1613.97 | 100 UG
DBCO-(PEG)3-VC-PAB-MMAE is an agent-linker conjugate for ADC, formed by conjugating Monomethyl auristatin E (HY-15162) to a DBCO-(PEG)3-vc-PAB linker. It can be used for cancer research and functions as a click chemistry reagent, containing a DBCO group that undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
- Agent-linker conjugate for ADC
- Click chemistry reagent
- Contains a DBCO group for SPAAC with azide groups
- For research use only
Medchemexpress LLC M-PEG-DSPE sodium | 95.0% | 3000 (average) | 25 MG
m-PEG-DSPE sodium (MW 3000) is a methoxy polyethylene glycol-distearoylphosphatidylethanolamine (PEG-lipid) provided as the sodium salt for use in drug delivery research. It is formulated to act as a surface-modifying lipid that improves colloidal stability and tissue targeting when incorporated into liposomes or nanoparticles.
- Provides hydrophilic PEG coating to reduce protein adsorption and extend circulation time.
- Average molecular weight of 3000 for predictable PEG chain length.
- Solid, white to off-white material suitable for formulation.
- High purity (95.0%) for reproducible experimental results.
- Compatible with nanoparticle and liposome formulation workflows.
- Store sealed at -20°C; solvent storage guidance for longer-term stability.
![Medchemexpress LLC 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid | 663921-15-1 | MFCD21607085 | 99.9% | 265.30 g/mol | C11H23NO6 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202923.png-250.jpg)
Medchemexpress LLC 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid | 663921-15-1 | MFCD21607085 | 99.9% | 265.30 g/mol | C11H23NO6 | 1 G
NH2-PEG4-CH2CH2COOH is an amine-terminated, four-unit polyethylene glycol (PEG) linker with a terminal propanoic acid. It is intended for use in bioconjugation workflows such as antibody-drug conjugate (ADC) and PROTAC linker synthesis and is supplied as an off-white to light yellow solid with high reported purity.
- cleavable four-unit peg linker suitable for ADC and PROTAC synthesis.
- amine-terminated functionality for facile conjugation to drugs or linkers.
- high purity (≈99.9%) for research applications.
- molecular weight around 265.30 g/mol and formula C11H23NO6.
- available in small research pack sizes (e.g., 100 mg-10 g).
- store sealed, away from moisture and light; for solutions store at -80°C (long term) or -20°C (short term).
Medchemexpress LLC E3 LIGASE LIGANDLINKER2(100MG)
Pomalidomide-PEG4-Ph-NH2 (Synonyms: Cereblon Ligand-Linker Conjugates 9; E3 Ligase Ligand-Linker Conjugates 2). Purity: >98.0%.CAS 1818885-63-0
eMolecules 20-(Amine-PEG3-ethylcarbamoyl)nonadecanoic-t-butyl ester | Broadpharm |572.872 | C32H64N2O6 | 0.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCN | 100mg | 784455341
20-(Amine-PEG3-ethylcarbamoyl)nonadecanoic-t-butyl ester | Broadpharm |572.872 | C32H64N2O6 | 0.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCN | 100mg | 784455341
Cayman Chemical Boc-NH-PEG3-OH 250mg
A PEGylated building block; has been used as a spacer in biotinylated heterobifunctional cross-linker agents; has been used as a spacer in near infrared imaging probes for CYP1B1, which is expressed in a variety of tumors; has also been used in the synthesis of graftable peptidomimetics that bind to human αVβ3 integrin and inhibit adhesion of human osteoprogenitor cells to vitronectin